What If DNA Shearing Took Minutes Not Hours

August, 2025 – Long prep cycles slow discoveries. Manual steps create drift. Heat can ruin precious DNA and protein samples. Many labs still rely on probe sonicators, ice baths, and multi-hour workflows. The industry needs faster, safer, and more repeatable methods. That is the pain point behind a simple question: What if DNA shearing took minutes, not hours?

Longlight Technology answers with a new generation of focused ultrasonication platforms and lab consumables. The company was founded in 2015 by university professors and market veterans. Its team has spent decades in molecular biology and molecular diagnostics. Since launch, Longlight has delivered China’s first focused ultrasonication sample system. It has also introduced the world’s first fluid vacuum degassing system. The mission is clear. Build world-leading biological laboratory equipment and lead fast-growing segments in the health market.

The centerpiece is the Focused Ultrasonicator Instrument line. It concentrates acoustic energy where it matters most: inside the sample tube. Energy is focused, not wasted. The water bath is non-contact and isothermal. That protects temperature-sensitive DNA, RNA, chromatin, and proteins. It also reduces contamination risk. There is no probe touching the sample. There is no need to open and close caps during processing.

For high-throughput genomics teams, the Focused Ultrasonicator Instrument offers 16 positions with flexible modes. You can process one sample or sixteen. Each sample can run a unique program if needed. Batch parameters make one-click runs easy. A sensitive temperature system keeps the sample zone stable. Logs allow full traceability. Automatic drainage simplifies maintenance. No external computer is required. This platform is an ideal DNA Shearing Ultrasonic System for next-generation sequencing. It delivers even fragment sizes, strong repeatability, and consistent libraries.

Clinical and microbiology labs face a different pain: tough cell walls. MALDI-TOF identification can struggle with mycobacteria and filamentous fungi. Traditional protocols call for ethanol inactivation and solvent wall-breaking steps. They are slow and messy. The Focused Ultrasonicator Instrument addresses this bottleneck. Add colonies to the sealed tube with extractant, then sonicate. Ultrasound enhances solubilization and speeds penetration through the wall. You can finish pre-treatment in about one minute of ultrasound and under five minutes total. Small inputs are enough. The closed-tube design lowers contamination risk for people and samples. Detection rates improve because more protein is released from fewer cells.

Protein interaction studies bring another challenge. Cross-Linking Mass Spectrometry (XL-MS) reveals protein-protein interactions and preserves weak or short-lived contacts. It offers high throughput and fast analysis. It works in cells and needs no special labeling. But the workflow can still feel complex for many labs. Longlight provides an XL-MS service option. Customers can send cross-linked samples or ask for a plan. The team completes digestion, enrichment, mass spectrometry, and data analysis. The deliverable is a clear report with interaction maps and sites of action. XL-MS data can also support cryo-EM or X-ray studies.

Chromatin research sees similar gains. ChIP and ChIP-seq need careful shearing to protect epitopes and generate the right fragment sizes. Focused ultrasonication brings tight control and low heat. That supports consistent pull-downs and clean libraries. The same applies to FFPE extraction, cell lysis, and tissue homogenization. The platform standardizes steps that once depended on operator skill and luck.

Speed matters after shearing as well. Many teams waste time pouring gels, mixing buffers, and waiting for runs. Longlight supplies molecular biology agarose gel in ready-to-use cassettes. Load samples and run. Typical separation completes in 10-20 minutes. The system is ethidium bromide-free and compatible with common mini tanks. Sensitivity reaches down to nanogram-level DNA. These gels are ideal for PCR checks, restriction digests, plasmid QC, and RNA quick looks. They shorten the loop from experiment to decision.

Longlight rounds out the workflow with consumables and kits. Options include nucleic acid extraction kits, library preparation kits, Qubit tubes, and scavengers. Together they form a practical supply chain for NGS and molecular diagnostics. The goal is stable quality, accessible pricing, and global service support.

What makes the Focused Ultrasonicator Instrument line different? It is the physics and the system design. Focused energy means less power wasted and less heat drift. Non-contact processing reduces contamination risk. True low-temperature control preserves integrity. Reproducibility improves across users and sites. That is a shift from legacy probe systems. It is also a shift from generic water bath devices that cannot focus sound accurately.

These instruments act as a Sonicator for Molecular Biology Labs of every size. Small labs gain automation and speed without a large footprint. Core facilities gain throughput and consistent performance. Biopharma and clinical labs gain traceability and validated runs. The result is faster prep, cleaner data, and fewer repeats.

Longlight Technology summarized the vision. “Researchers should not lose a day to sample prep. Our systems bring shearing and lysis into a short, stable window. Minutes, not hours. That time goes back to science.”

Key advantages for teams adopting the DNA Shearing Ultrasonic System and related tools:

•  Minutes-level shearing for NGS libraries.
•  Tight fragment control and low heat exposure.
•  Closed-tube workflows that reduce contamination.
•  Multi-sample throughput with per-well programs.
•  Traceable runs and automated maintenance features.
•  Faster confirmatory checks using ready-to-run gels.
•  Integrated support for proteomics and chromatin studies.

Longlight’s roadmap remains focused on genomics, proteomics, and molecular diagnostics. The R&D team continues to refine acoustics, temperature control, and UI design. The goal stays the same. Turn complex sample prep into predictable, fast, and safe routines.

So, what if DNA shearing took minutes, not hours? With focused ultrasonication, it does. With smarter consumables, results arrive sooner. With service support for XL-MS, proteomics becomes approachable. Longlight Technology invites labs to test the difference and measure the gains.

In the end, speed is not the only win. Stability is. Reproducibility is. Safety is. That is how modern labs move from backlog to breakthrough. That is how Longlight Technology helps teams turn today’s questions into tomorrow’s answers.

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Organization: Longlight

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Website: https://www.longlight.com/

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Contact Number: +8675586727654

Address: No. 202, Block B Nanfeng Building, Nanshan Yungu Innovation Industrial Park, Liuxian Avenue, Nanshan District, Shenzhen, China

Country: China

Release Id: 16082532421